The competition, sponsored by an internationally respected health care organization Sanford World Clinic, will involve all 16 National Women's League clubs and clubs representing the various regions.
The preliminary round of the competition was played earlier this month to select the teams that will represent the regional league clubs in the round of 32 stage.
Sanford World Clinic signed a four-year agreement worth GH¢1.1million with the Ghana Football Association with an interest in helping the GFA develop the talents of young girls across the country through football.
Police Ladies won the maiden edition of the competition played at the new Cape Coast Stadium.
Credit: Ghana FA